CO₂ vaginal rejuvenation uses a fractional carbon dioxide laser to prompt the body’s own tissue renewal process in the vaginal canal. Aspen Aesthetics + Wellness performs this treatment with the RejuVAnate, a fractional CO₂ handpiece by Rohrer Aesthetics built specifically for intimate tissue. RejuVAnate is a fractional CO₂ that targets water in the deepest parts of the dermis, prompting a controlled healing response without incisions or surgical downtime.
People often consider CO₂ vaginal rejuvenation when they notice changes in dryness, discomfort, loss of sensation, or loss of bladder control after childbirth or menopause. It is a non-surgical, in-office option, but it remains a medical procedure that requires screening, sterile technique, and realistic expectations. A private consultation can clarify whether CO₂ vaginal rejuvenation or another approach fits your concerns.
Clinical authority
Kelly McKay, MSN, APRN, CRNA, is Aspen Aesthetics + Wellness’ Clinical Director. Care is provided under her medical oversight, and treatment is performed by a trained, licensed provider after a private health review and discussion of risks, expectations, and alternatives.
CO₂ refers to carbon dioxide, the laser medium used to deliver energy to tissue. A fractional laser treats tissue in a controlled pattern of microscopic zones rather than across the full surface at once, which limits trauma while still triggering the body’s natural repair response. Vaginal rejuvenation at Aspen uses the RejuVAnate to apply this energy directly to the vaginal canal in a private, in-office setting.
The laser energy is absorbed by water within the tissue. This heats the treated zones and prompts fibroblasts, the cells responsible for collagen production, to begin the body’s natural remodeling process. The goal is to support tissue integrity, lubrication, and overall vaginal health over the weeks following treatment.
CO₂ vaginal rejuvenation does not replace gynecologic or urologic evaluation. Pain, bleeding, recurrent infections, or significant urinary symptoms should be assessed medically before an elective procedure.
Interest in CO₂ vaginal rejuvenation often centers on comfort and quality of life. These are sexual health concerns, and candidacy depends on symptoms, health history, and whether established care should come first.
Vaginal rejuvenation and menopause are often discussed together because lower estrogen levels can contribute to dryness, irritation, tissue changes, and discomfort. Clinicians refer to this cluster of symptoms as the genitourinary syndrome of menopause, or GSM. Interest in CO₂ laser treatment for vaginal dryness has grown as researchers examine nonhormonal options for women who cannot use or prefer not to use hormonal therapy.
Childbirth, aging, hormones, and pelvic-floor health can all affect vaginal tissue tone and sensation. CO₂ vaginal rejuvenation is sometimes discussed when tissue support appears relevant, though it cannot guarantee a specific change in sensation for every patient.
Stress urinary incontinence is leakage with coughing, sneezing, laughing, lifting, or exercise. Some research on fractional CO₂ laser has examined its effect on mild urinary symptoms alongside vaginal tissue changes, though results across studies are inconsistent. Worsening or unexplained leakage needs medical evaluation rather than an elective procedure.
Patients often ask, “Does CO₂ vaginal rejuvenation work?” The honest answer is that the evidence is mixed, and it depends on which outcome is being measured.
A 2023 systematic review and meta-analysis of seven randomized, sham-controlled trials found that CO2 laser treatment produced a significant improvement on a general vaginal assessment scale for GSM symptoms, but was not significantly different from sham treatment on several other measures, including sexual function scores, pain during intercourse, vaginal health index, and vaginal pH. A more recent 2025 review of that same body of sham-controlled trial evidence concluded that current data do not support fractional CO₂ laser as an effective treatment for GSM specifically.
This uncertainty is part of why the U.S. Food and Drug Administration issued a 2018 safety communication cautioning that it has not cleared or approved any energy-based device, including CO2 lasers, to treat symptoms related to menopause, urinary incontinence, or sexual function, and that the safety and effectiveness of these devices for those specific uses have not been established.
None of this means CO₂ vaginal rejuvenation cannot help. It means results are not guaranteed, and the research base is still developing. A private consultation is the right place to discuss what the evidence does and does not show for your specific concerns, alongside other proven options.
Treatment starts with a private consultation and health review. Your provider will explain what CO2 vaginal rejuvenation involves, answer questions, and confirm whether you are a candidate before scheduling a session.
Treatment is performed in a private room. The RejuVAnate is used to deliver laser energy directly to the vaginal canal, and your provider will walk you through preparation, comfort measures, and aftercare specific to your plan. Ask about current pricing, membership, and packages during consultation.
Most people begin with a series of three CO₂ vaginal rejuvenation sessions, spaced four to six weeks apart. Some people may need additional sessions, since the right number is patient-dependent. A comprehensive consultation is when your provider confirms the treatment plan that fits your goals.
Intimate treatment requires appropriate screening, sterile technique, provider training, privacy, and clear follow-up.
Kelly McKay, MSN, APRN, CRNA, serves as Aspen’s Clinical Director. Aspen states that delegated clinical services are performed under her supervision and standing orders in accordance with Colorado HB 25-1024. This supports clinical accountability while a trained, licensed provider performs care.
Medical oversight also supports appropriate referrals. Some symptoms require gynecologic, urologic, hormonal, or pelvic-floor evaluation before elective care.
Sensitive health changes deserve a private, respectful conversation. Aspen can review your concerns, explain vaginal rejuvenation at Aspen, and discuss whether CO₂ vaginal rejuvenation or another next step may be appropriate.
CO₂ vaginal rejuvenation should begin with realistic expectations and a clinical evaluation. To ask questions, confirm current pricing, and receive clinically guided information without pressure, book a private consultation.
This was my first ever chemical peel, and Kelly was great! She is so educational and helpful in explaining the process and all of the following steps + skincare. I can’t wait to see my results and follow up with her again!
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